Moscow, Spectr Publishing House, 2012. — 344 s. The theoretical foundations of the integrated design of flexible energy- and resource-saving chemical-technological processes are presented , devices and systems using methods of system analysis , mathematical modeling and optimization of complex HTS in conditions of interval uncertainty of the initial data . The basic concepts of the theory of flexibility are outlined and the tasks of integrated design of flexible energy and resource-saving HTS are formulated depending on the level of available experimental information about the technological process during its implementation and possible control tools. Designed for chemical technologists and design engineers of chemical-technological equipment, researchers, graduate students and teachers of technical universities in the field of system analysis, mathematical modeling, optimization and design of HTS .