Training Manual . - Tambov: TSTU, 2005. Various aspects of computer modeling of biotechnological processes and systems are considered - from problem setting and development of mathematical models to their computer implementation and interpretation of the obtained results. General information about mathematical models and computer modeling is given, the modern methodology of computer modeling of biotechnological processes and systems is presented. Mathematical models of kinetics of processes of continuous cultivation of microorganisms, biotransformation and biocatalysis, membrane separation of biosynthesis products, biotechnological processes in medicine are presented . Intended for full-time and part-time students of specialties "Food Biotechnology" , "Main processes of chemical production and chemical cybernetics" , "Machines and Apparatuses of Food Production" , "Machines and apparatuses of chemical production" and undergraduates of the direction "Technological machines and equipment" . Approved by the Academic Council of the University as a teaching aid for students of specialties 240801, 240902, 260601 and undergraduates of the direction 150400 full-time and part-time forms of education .