The book is devoted to one of the new and promising directions of computer analysis of tomographic images - methods of analysis of three-dimensional (volume) textures. These methods are based on the use of multivariate co-occurrence matrices that combine the brightness, gradient and orientation properties of images. The use of the proposed apparatus is illustrated by the example of the tasks of quantitative analysis of MRI images of the brain, the combination of three-dimensional medical images, as well as the tasks of searching for images in databases by their content. The target audience of the book are scientists and specialists working in the field of medical informatics, as well as in the field of systems for processing and quantitative analysis of three-dimensional images with application to the tasks of medical diagnostics. In addition to , This book can be useful for researchers and specialists, Computed Tomography , Radiology , Neuroscientists , as well as students of relevant specialties , professional activities and scientific interests of which are closely related to the use of computers in medicine .