The manual is compiled in accordance with the program on medical genetics. Sufficient information is provided on the main sections of the subject, Issues of General Genetics , Features of clinical and morphological examination and analysis , Methods of research, General and specific , Testimony to them , Classification and Characterization of Inherited Diseases , Congenital malformations , Primary malabsorption syndrome . for all described nosological units are given codes ICD-10. The annexes present the most common diseases and syndromes (for all the described nosological units, ICD-10 codes are given), a dictionary of genetic terms. When compiling the manual, modern sources, publications of recent years, periodicals . are used. The manual can be used by students and interns in the study of the subject, pediatricians, neonatologists, obstetricians-gynecologists and doctors of other specialties in practice.