The Siberian Oncological Journal . Volume 16 No. 4 2017”, created by a team of specialist authors, is an important and relevant publication that will become a valuable resource for oncologists, medical researchers and specialists interested in the latest achievements in the field of oncology. This issue is not just a collection of articles, but a real bridge between scientific theory and practical medicine, offering fresh views on the diagnosis, treatment and prevention of cancer. The focus of this issue is on complex studies devoted to various aspects of oncology, ranging from molecular mechanisms of cancer development to new methods of therapy. A special place is occupied by the analysis of modern diagnostic methods, such as molecular genetics and immunotherapy, as well as the discussion of clinical cases that demonstrate the effectiveness of new approaches. The authors, including leading specialists of the Siberian region and the country as a whole, share the results of their research, which makes this journal not only a source of theoretical knowledge, but also a practical guide for oncologists facing real challenges in their work. The Siberian Oncological Journal . Volume 16 No. 4 2017” is perfect for medical professionals, undergraduates and graduate students, as well as for anyone interested in modern trends in oncology. Readers interested in medical science will find here not only relevant articles, but also analytical reviews that help to understand the complex processes underlying the development of tumors, and choose the most effective methods to combat them. This release is especially valuable for those looking for fresh ideas and innovative approaches based on the latest scientific evidence. The topics raised in this issue cover a wide range of issues, from the molecular aspects of cancer and genetic predisposition to new chemotherapy and radiotherapy methods. Particular attention is paid to the development of personalized medicine, which is becoming increasingly important in the fight against cancer. The authors analyze in detail the cases of successful use of immunotherapy and targeted drugs, emphasizing the importance of an interdisciplinary approach and teamwork in cancer practice. An important part of the journal are reviews of new technologies and diagnostic methods, which makes it an indispensable assistant for those who want to stay up to date with the latest scientific achievements. The style of the publication is characterized by strict scientific accuracy, but at the same time it is available to a wide audience of specialists. A team of authors with rich experience and deep knowledge writes so that the information is understandable and the ideas are inspiring. This issue shows the desire for constant development and improvement of methods of fighting cancer, which makes it not only a scientific source, but also an incentive for further research and practical solutions. If you are looking for a book that will help you understand current trends in oncology, expand your knowledge and find new ideas for practical work, "Siberian Oncology Journal. Volume 16 No. 4 2017" will be a great choice. This publication is not just a collection of articles, but a living document reflecting the dynamics of the development of cancer science, and an important contribution to the fight against one of the most complex and urgent challenges of modern medicine.