According to expert reports, a third of the world's population met with viral hepatitis B (HBV) . About 300-350 million people are asymptomatic carriers of this virus. It is endemic, spread worldwide, except in isolated populations, a viral infection with very high levels of virus carriers (up to 20%), especially in South and Southeast Asia. The incidence of acute hepatitis B is 1:100,000 in Northwestern Europe, 6:100,000 in Southwestern Europe, 22:100,000 in Central Europe, and 92:100,000 in Eastern Europe, although the true incidence is probably several times (up to twice) greater. Up to one million acute cases of HBV and 90,000 newly diagnosed cases of chronic HBV. are reported in Europe each year. Chronic transmission of the virus occurs in 5% of the population in Southern Europe, 0. 01-0.5% in Northern Europe and much higher prevalence observed in at-risk groups. Viral hepatitis C is endemic worldwide and has a high prevalence in South, East Asia and Eastern Europe...