Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

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"Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals" contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures. The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment. It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routes - both oral and dermal - as well as risk assessors in the government, academe, and private industry.
LF/627463/R

Data sheet

Name of the Author
Board on Environmental Studies and Toxicology
Committee on Toxicology
National Research Council
Subcommittee on Acute Exposure Guideline Levels
Language
English
ISBN
9780309570114
Release date
2001

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Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

"Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals" contains a detailed and comprehensive methodology for ...

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