There are many books about healthcare, technology, and even healthcare information technology. However, none of those other books rival the one you hold in your hands (literally or figuratively) at better representing the current collective knowledge and experience of healthcare information systems experts. Within the chapters of this text, you will encounter nurses, physicians, informaticists, technologists, researchers, analysts, educators, scientists, and many others with titles and positions that represent the broad world of healthcare information professionals. The scope of their experience spans the globe and represents the best and brightest our professions have to offer. Many I am privileged to know as friends, others I know by reputation, and I welcome you to partake in their collective wisdom through this text.This volume offers the opportunity for students, professionals, and leaders who are responding to a calling to care to walk through a door of understanding into a room of knowledge. This knowledge represents the exponential impact that healthcare information systems bring when designed, implemented, and used well for the power of healing. Information is the lifeblood of healthcare and technology is the catalyst for information efficacy.