The book "Mechanisms of regulation of coronary blood flow mediated by endothelial vasodilating factors" by B. and . Kozlovsky is a deep and comprehensive study that immerses the reader in a complex but incredibly important world of the cardiovascular system. This scientific work is intended for specialists in the field of cardiology, physiology, medicine and biomedicine, as well as for those who seek to understand the intricacies of the functioning of the heart and blood vessels at the molecular and systemic levels. However, the book can also be of interest to students, graduate students, as well as everyone who is passionate about modern medical discoveries and wants to expand their knowledge about the regulation of blood flow in the heart. The book focuses on the role of endothelial vasodilators, which are key elements in maintaining a balance between constriction and dilation of the coronary vessels. Author, B. and . Kozlovsky , well-known specialist in the field of vascular physiology and cardiology, masterfully reveals the mechanisms, underlying regulation of blood flow, Showing, how endothelial cells interact with muscle layers of blood vessels, by adjusting their diameter and, Therefore,, Blood supply to the heart muscle . This book is a unique source of knowledge that combines modern scientific achievements with practical aspects of the diagnosis and treatment of cardiovascular diseases. By reading “Coronary blood flow regulation mechanisms mediated by endothelial vasodilators,” you are immersed in the fascinating world of biochemistry, physiology, and pathophysiology. The author examines in detail the role of nitric oxide (NO), prostaglandins, endothelin and other substances, revealing their functions and interactions in the blood flow regulation system. Particular attention is paid to the mechanisms that allow the heart to adapt to the changing needs of the body, as well as those that underlie the development of various pathologies - hypertension, atherosclerosis and coronary heart disease. This book not only expands the horizons of knowledge, but also helps to understand how modern methods of diagnosis and therapy use these mechanisms to combat cardiovascular diseases. Book B. and . Kozlovsky is not just a collection of scientific facts, but a vivid and lively narrative, saturated with examples and illustrations that make complex topics accessible and understandable. The style of the author is characterized by accuracy and logical consistency, which allows the reader to easily follow the development of thought and assimilate the material. In his other well-known works, such as studies in vascular physiology and pathophysiology, he demonstrates a deep understanding of the topic and the ability to explain complex processes in a simple and fascinating language. This book is ideal for those who want to understand how the vessels of the heart work, what mechanisms underlie their regulation and how modern scientific discoveries help fight cardiovascular diseases. It will be of interest to both experienced specialists and medical students who want to deepen their knowledge. The topics raised in the book are important for understanding modern methods of treatment and prevention of coronary heart disease, hypertension and other diseases associated with impaired blood flow. If you are looking for a book that combines scientific rigor and practical value, and also reveals the secrets of vascular regulation at the molecular level, “Mechanisms of regulation of coronary blood flow mediated by endothelial vasodilating factors” B. and . You will be a great source of knowledge for them.................. This work will not only expand your understanding of the work of the heart, but also inspire new research and discoveries in the field of medicine and physiology.