The monograph covers experimental materials, by , that in the conditions of a technogenic zone to increase milk productivity , improvement of physicochemical and technological qualities of milk and dairy products , as well as to increase the profitability of dairy production, it is advisable to use the enzyme drug protosubtilin GZh , in the diets of cows of the black-and-white breed sorbent toxin and antioxidant vitamin C. Based on the results of two scientific production and two physiological exchange experiments on lactating cows, the effect of these biologically active additives on their milk productivity was studied. physico-chemical and technological properties of milk , digestibility and digestibility of nutrients , cicatricial and intermediate exchange activity , reproductive functions of experimental animals and profitability of milk production under denitrification conditions. For researchers and students of zooveterinary and biological profile .