This edition offers readers five articles about cocaine and cocaineism of the great Austrian psychologist and psychiatrist, the founder of psychoanalysis Sigmund Freud. The young scientist spent quite a bit of time studying the medical properties of coca At first, Freud considered cocaine an antidepressant in both somatic and psychological relationships. Freud experienced both effects on himself, as he later explored the unconscious through introspection. Later, the scientist will declare cocaine a dangerous drug and abandon further research in this area, not without difficulty getting rid of cocaine addiction. Articles included in this collection are rarely published because they do not represent pharmacological value, although it was under the influence of Freud's experiments that cocaine began to be used in eye surgery. Their main significance lies in the fact that they testify to the awakening of young Freud’s interest in the unconscious, which later became the main topic of the scientist’s research.