Pancreatology is one of the most important sections of modern gastroenterology, due to the key role of the pancreas in the food-cooking "conveyor" In its formation and development, pancreatic science, like any clinical discipline, has come a long way from describing individual symptoms characteristic of pancreatic diseases, to in-depth fundamental research involving the achievements of other sciences. The successful development of pancreatic medicine in Russia is largely due to the union of physiologists and clinicians characteristic of Russian medicine. The pancreas has always attracted the attention of doctors and researchers. The first mention of PJ dates back to the 3rd century BC. e. and attributed to Aristotle (in the book "History Animalium"). However, the study of physiology and pathology of PJ for many years remained a very difficult task. which was due to the topofaphoanatomical features of this organ and hidden , the non-specific nature of the manifestations of most of its diseases , Especially in the early stages.... as well as the lack of objective methods for its assessment [9]. According to a well-known specialist in the field of pancreatic G. F. [12] The pancreas slowly and reluctantly revealed its secrets. Prominent physiologist P. Heidengain believed that PJ scientists would leave this area of research without regret and without great achievement (cit.) by[10]. In the well-known manual on internal diseases M. P. Konchalovsky (1935) it is said that diseases of PJ are not so often and are even more rarely recognized at the patient's bedside; more often the diagnosis is made on the operating or even sectional table . Here is an example of recognition .. Kera (Kehr), who in the first 900 patients operated on for diseases of the biliary tract, did not see any pancreatitis, and among the following 540 cases he found 102 cases of chronic pancreatitis only because he was looking for them [11]. Significant progress in the study of pathology occurred at the turn of the XIX-XX centuries and was largely due to the achievements of the physiology of digestion.