This book addresses the challenges of automated design for the most complex and labor-intensive stage of chemical plant engineering—the development of an optimal plant layout. It covers the process of determining the configuration and dimensions of the facility, as well as the ideal placement of equipment, pipelines, and valves within the plant. Designed for students specializing in "Machines and Equipment for Chemical Production" (code 240801), "Design of Technological Machines and Complexes" (code 151701), and for those studying disciplines such as "Flexible Automated Production Systems in Chemical Technology" and "Automated Production Systems." It also serves as a valuable resource for master's students in "Systems Analysis and Control" (code 220100), as well as postgraduate researchers in areas like "Mathematical Modeling, Numerical Methods, and Software Complexes" (code 05.13.18) and "Systems Analysis, Control, and Information Processing" (code 05.13.01).