The recommendations included in the Handbook are compiled by leading Russian experts on the basis of the most up-to-date information, the reliability of which has been proven by numerous qualitative studies. Clinical recommendations are especially convenient for a medical practitioner who has his own experience and takes into account the individual characteristics of each patient in his daily activities. Recommendations are distributed in alphabetical order in 4 sections: “Symptoms and syndromes”, “Diseases”, “Emergency conditions”, “Reference section” The data on differential diagnosis of various symptoms and syndromes, treatment of about 100 diseases, as well as on urgent diagnosis and therapy of life-threatening conditions of the patient. are given. The "Reference section" includes ICD-10 codes, a directory of laboratory and instrumental standards (including ultrasound, FWD, etc.) ) and a directory of all international and trade names of medicines allowed for use in the territory of the Russian Federation as of 30. 10. 2004. The publication is intended for practicing therapists, district doctors, general practitioners, as well as interns, residents and senior students of medical universities .