The manual is focused on the use of computational and experimental methods to ensure the strength of structures , The basic characteristics of more than 70 grades of steels and alloys with the help of the proposed mathematical models allow to calculate the processes of deformation and low-cycle destruction under arbitrary loading programs. For materials not included in the reference, these characteristics can be determined by the user himself using the recommended method using experimental cyclic deformation diagrams and creep curves. Addressed to engineers, researchers, graduate students and university students engaged in the design, testing and operation of high-load and thermal-voltage structures, as well as the study of the properties of materials .