Computer Assisted Modeling - Contributions of Computational Approaches to Elucidating Macromolecular Structure and Function.
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In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule,polymers formed from families of simpler subunits. Because of their size and complexity, the polymers are capable of both inter- and intramolecular interactions. These interactions confer upon the polymers distinctive three-dimensional shapes. These tertiary configurations, in turn, determine the function of the macromolecule. Computers have become so inextricably involved in empirical studies of three-dimensional macromolecular structure that mathematical modeling, or theory, and experimental approaches are interrelated aspects of a single enterprise..
LF/714411/R
Data sheet
- Name of the Author
- Assisted Modeling
Commission on Life Sciences
Committee on Computer
Division on Earth and Life Studies
National Research Council - Language
- English
- ISBN
- 9780309062282
- Release date
- 1987
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In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucle...