The training manual covers issues related to the structure and functional activities of the respiratory system. The history of the development of respiration is given, the issues revealing the structure of the respiratory organs, their functional activity, the peculiarities of respiration in various conditions and the mechanisms of regulation of the respiratory system . are considered. Drawings and diagrams are used to illustrate the material, and some of the material is presented in tables. At the end of the manual, questions are given for self-examination of knowledge. The manual is designed for students of all profiles in the direction of training "Biology", and can also be useful for students of medical specialties, undergraduates, graduate students and teachers who want to expand their knowledge of breathing .