Presented articles of students and graduate students of the Faculty of Economics of RSU . and . Kant, who continue a series of publications on the problems of development of the Kaliningrad region . The results of research devoted to the development of industries of regional specialization, infrastructure and life support industries, as well as the development of entrepreneurship and market environment, integration and cross-border cooperation in the exclave region of Russia are considered. Addressed to specialists and practitioners dealing with the problems of economics and management of regional and territorial entities .