This manual highlights the state of the problem of chronic pelvic pain syndrome in patients with external genital endometriosis, outlines the issues of pathogenesis, as well as the diagnosis and treatment of chronic pelvic pain. In addition, issues of the influence of the autonomic nervous system on the mechanisms of chronic pain syndrome in this category of women are indicated. The manual proposes methods for the examination of vegetative status, the principles and regimens for the treatment of chronic pelvic pain. The manual is intended for postgraduate training of doctors in the specialties "Obstetrics and Gynecology" and "Nervous Diseases", contains drawings, tables, test tasks and situational tasks.