The monograph is devoted to the actual problem of managing crop parameters in the conditions of natural and artificially created heterogeneity of parameters of fertility of agricultural lands , variation of biomass and elemental composition of plants depending on the phase of development, Genetically determined species and varietal characteristics. Shown, that in order to effectively manage the production process and the quality of crops, it is necessary to have knowledge of the laws of plant growth and development in changing soil and climatic conditions and the laws of accumulation of macro- and microelements in the soil and their distribution in the soil-plant system. To identify these patterns, information is needed about the dynamics of these processes, the establishment of time-response dependencies and dose-response. Concepts of spatial and temporal heterogeneity of biomass and elemental composition of plants are considered. Information on the existing methods for assessing the spatial and temporal variability of biomass and elemental composition of crops within the field and the plot of field experience is summarized, criteria for assessing these parameters are formulated. A methodological approach is presented that allows to quantify the influence of heterogeneity of soil and seed parameters on the spatial and temporal variability of biomass and elemental composition of plants. Quantitative assessment of the effect of mineral and organic fertilizers on the maximum take-off and maximum rates of removal of mineral nutrition elements by plants. Methods for assessing the spatial and temporal heterogeneity of crops illustrate the results of field and model experiments.