Selected lectures on biophysics given by prof. Yu. A. Vladimirov for students of the Faculty of Fundamental Medicine of Moscow State University . Basic equations of thermodynamics. Thermodynamic Probability and Entropy . Relation of equilibrium constant to free energy change. Temperature dependence of equilibrium (Gibbs equation). Work and Energy . Basic Sweating Bioenergy: Systems and Objects, Power, Work, Energy. Electrochemical potential . Phase transitions of lipids in membrane. DSC Method. Heat capacity curves parameters. Melting curve measurement methods. Biological Thermodynamics . Conversion of energy into a living cell . Experimental determination of thermodynamic parameters of biosystems. Features of living organisms as thermodynamic systems .