The textbook, based on the achievements of agrochemical science, presents new experimental data on improving the effectiveness of fertilizers in the relationship of factors "soil, climate, fertilizer and plant" .. Much attention is paid to the role of agrochemistry in regulating plant nutrition in order to increase yields and the quality of crop production, as well as in the reproduction of soil fertility, improving the balance and biological cycle of substances. All these issues are considered taking into account the peculiarities of natural and climatic conditions .. New environmental functions of agrochemistry are formulated. The scientific foundations of zonal fertilizer systems and individual crops, their agronomic and environmental assessment are presented . For students of soil specialties of universities, as well as for students of agricultural universities