Handbook of Space Biology and Medicine, edited by A. and . Burnazian and O. G. Gazenko, is a unique and in-depth study at the intersection of science and practice, devoted to the issues of biology and medicine in space. This edition will be an indispensable resource for everyone who is interested not only in space, but also in how life adapts and functions in extreme conditions. The guide covers a wide range of topics, ranging from physiological changes occurring with the human body in microgravity, and ending with the issues of medical support for astronauts. The authors, including such famous scientists as Avetik Ignatievich Burnazyan and Oleg Georgievich Gazenko, share their knowledge and experience accumulated over decades of research in the field of space biology. They raise important questions about how spaceflight affects human health, what diseases can occur in conditions of prolonged stay in space and how to minimize health risks. The book will be of interest not only to specialists in the field of medicine and biology, but also to a wide range of readers, including students, graduate students and everyone who is fond of cosmonautics. It can be a useful tool for future astronauts, researchers and anyone who dreams of traveling in space. Readers interested in the topics of health, medicine, as well as human adaptation to new conditions will find in this guide a lot of useful information. One of the key themes of the book is the adaptation of man to the conditions of space. The authors consider in detail how long flights affect the cardiovascular system, musculoskeletal system and other important functions of the body. They also discuss the health effects of space radiation and methods of protection against it, which is an urgent issue for future interplanetary missions. These aspects make the book particularly valuable in light of current research and plans to colonize other planets. The style of the authors is distinguished by the scientific rigor and accessibility of the presentation . They skillfully combine complex scientific concepts with practical recommendations, which allows the reader not only to understand, but also to apply the knowledge gained. There are many illustrations and tables in the book, which makes the material more visual and easy to perceive . The Handbook of Space Biology and Medicine also echoes other well-known works in the field of space medicine, such as Space Medicine and Human Adaptation to Space Conditions. These works, as well as this guide, emphasize the importance of an interdisciplinary approach to the study of life in space, combining biology, medicine, physics and psychology. This book is not just a reference book, but a real encyclopedia of knowledge that opens doors to the world of space research and medical technology. It inspires us to think about the future of humanity in space and how we can overcome the barriers that stand in the way of the stars. If you want to learn more about how life can exist and evolve in conditions far from the usual, the Handbook of Space Biology and Medicine will become your reliable guide in this fascinating and mysterious world.