The textbook corresponds to the state educational standard of higher professional education in the direction of training of certified specialists 654600 - "Computer Science and Computer Engineering" (Specialty 220100 - "Computers, complexes, systems and networks"). The manual provides a classification, a brief description of the capabilities and applications of microprocessors. The options for building the architecture of microprocessor (MPS) and multimicroprocessor systems, their main configurations and areas of use. are considered. Particular attention is paid to the organization of subsystems of processing, control, memory and input-output of MPS. The main tasks of the design of the MPS are considered, including the organization and design features of the MPS based on single-chip microcomputers and controllers . Information on means of development, testing and debugging of MPS. The manual also contains a brief overview of the history of the development of microprocessor tools, the current state and promising projects of the MPS .. The textbook is intended for fifth-year students studying the discipline "Microprocessor systems"