The textbook discusses the quantum properties of radiation, the foundations of quantum optics, elements of quantum mechanics, atomic and nuclear physics and particle physics. The main attention is paid to the explanation of the fundamental laws, phenomena and concepts associated with this section of the course of physics .. The manual was prepared at the Department of General Physics of Tomsk Polytechnic University, corresponds to the program of the physics course of higher technical educational institutions and is aimed at activating scientific thinking and cognitive activity of students. Designed for interuniversity use by students of technical specialties of full-time and distance forms of education .