The proposed book is a fundamental textbook on biophysics, which outlines the foundations of modern biophysical science. The first volume gives the theoretical foundations of biophysics. A significant place is given to the problems of mathematical modeling of biological processes at different levels of the organization of living things. The physical features, dynamic and electronic properties of the structural unit of the living - macromolecule, as well as physico-chemical mechanisms of energy transformation in biostructures . are considered. In the second volume (see .) 15-30) consider the physico-chemical mechanisms of the most important processes occurring in organisms. The issues of structure and functioning of biological membranes, bioelectrogenesis, muscle reduction of electron transfer reception and energy transformation in biomembranes are covered in detail . Mechanisms of primary stages of photobiological processes, including photosynthesis, vision, and photochemical reactions in biopolymers are considered. For students, graduate students and generalists interested in the physico-chemical foundations of life processes .